The Pick of Destiny
In the film, Black eats mushrooms and starts to hallucinate, and subsequently meets Sasquatch. The two hold hands, with Black becoming Sasquatch's son, 'Baby Sas'. The two sing and go down the 'Strawberry River', when in reality, Black is drowning in some form of river or lake. The two then start to fly, with Black on Sasquatch's back. Whilst air-borne, Black thinks that he has spotted 'The Pick of Destiny' and therefore reaches out to grab it, however, falls out of a tree and subsequently wakes up. The song sang is released on The Pick Of Destiny as "Papagenu (He's My Sassafrass)".
- John C. Reilly is credited as a 'Sasquatch Researcher' in the Pick of Destiny credits.
- Starting on the Rize of the Fenix Tour in 2012, Kyle Gass Band lead singer Mike Bray dresses up as 'Tenacious D Sasquatch' and performs "Papagenu (He's My Sassafrass)" live. In later 2012, he would go on to perform as a support act, performing his own songs solo, including 'Strawberry River' - a tribute to the film.